Furthermore, the majority of fibrinogen concentrate studies (76%) were of low quality and did not report the effect of the intervention in relation to a comparator group.
In total, 18 of 20 outcomes indicated no reduction in blood loss (primarily reported as postoperative blood loss) for the FFP group in relation to the comparator group [ 23, 35- 50] (Table 5).
Whether the points in the scatter plot indicate that recombinant follicle-stimulating hormone is cost-effective in relation to its comparator depends on the willingness to pay per birth achieved.
25 43 Summary measures will be presented along with sampling uncertainty to describe the best estimate of the costs and effects of the treatment groups in relation to the comparator.
Since a drug cannot be cost-effective in itself, but only in relation to a defined comparator and for a defined indication, HTA can be used to restrict reimbursement within the licensed indications [ 24].
For each comparison, the table shows the estimated mean incremental cost effectiveness ratio, plus the likelihood of the nominated management option generating higher costs, higher benefits, or acceptable cost effectiveness in relation to its nominated comparator.
Likewise, there was little difference between the three comparators in relation to overall survival, with median survival times varying from 36.7 to 54.3 weeks (Main et al, 2006).
Comparative subgroup analyses of daptomycin and vancomycin were conducted to determine the drug's rate of clinical success; the same was carried out for daptomycin versus comparators, in relation to treating Staphylococcus aureus, to determine its microbiological success.
We directly assessed variability in outcome related to comparator antidepressant by producing forest plots of the primary outcome examining each comparator in turn (fig 10).
Citigroup's overall improved stance on UK domestic banks was based on "recent macroeconomic, industry and comparator evidence of positive trends in relation to UK loan impairments, margins, wealth management product sales and investment banking earnings".
