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Methodological challenges are discussed in regard to sampling issues, the management of data, data analysis and validity checks.
In regard to sampling, the following three aspects were taken into consideration.
This finding indicates that there are substantial differences in the regulation of the transcriptome in regard to sampling time and sample origin, and demonstrates that the within-group-variability was sufficiently low to allow the separation of the groups.
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In regard to sample heterogeneity, the findings here apply only to those individuals reporting higher levels of cognitive anger.
Studies presented high risks of bias, particularly in regard to sample representativeness, and confounder identification and adjustment.
Furthermore, the comparison of substantial subgroups that do not differ too much in regard to sample size was intended and led to the age groups mentioned above.
In regard to sample HBV-2717, the OD of the laboratory EIA with antigen was 0.293, very near the acceptable minimum, and the background was 0.027, which is very low; this sample was considered provisionally positive.
Polymerase Chain Reaction based tests offer potential for continued development, particularly in regard to sample preparation, to further improve upon sensitivity, automation, throughput and to achieve improved cost-effectiveness.
Potential misinterpretation of the concept of biobanking in regard to sample storage for the relatively short period between collection and analysis means sample storage practices within the projects underway probably ought to be re-evaluated according to Article 19 of Law no.
Electrochemical techniques offer considerable potential for applications in the biological sciences, particularly with regard to sampling chemical gradients in the diffusive boundary layer surrounding cells and tissues.
With regard to sampling depth in the training set, the argument may be academic: the large number of possible combinations would be impractical to survey in the laboratory, and also appears to be sparsely populated in nature (data not shown) (Berger et al., 2008).
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