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PD results revealed that the two tested formulations were equally effective in reducing low density lipoproteins (LDL) and triglycerides (TG) levels when given in reduced doses compared to Lipitor® and showed no adverse effects.
An additional factor to take into consideration when using these drugs is that DPP-4 inhibitors (in reduced doses) are safe for treating patients with moderate and severe renal failure, whereas GLP-1 analogs are contraindicated in these patients.
Thus, antibiotics used in combination should not be administered in reduced doses.
Propranolol was withdrawn 2 months after, and propylthiouracil was maintained in reduced doses for 5 years when radioiodine therapy was performed.
Similar(56)
In those patients lenalidomide was administered in reduced dose of 5 mg on days 1 28 for two cycles.
(i) The addition of regorafenib to standard treatment with FOLFOX or FOLFIRI may have resulted in a higher frequency of dose reductions and interruptions, resulting in reduced dose intensity.
For RG108, infection in the vehicle only-treated cultures did not alter normal bacterial growth, with propagation of 5-fold by 72 h (Fig. 2b); however, treatment with all doses of RG108 resulted in reduced dose-dependent bacterial growth at 48 and 72 h posttreatment.
To the best of our knowledge, no study to date has examined the effect of recently available iterative reconstruction techniques, developed with the aim of reducing image noise in reduced-dose CT images, on image quality and diagnostic performance of non-contrast CT in the setting of acute renal colic.
Usually, patients take them in much reduced doses or intermittently, but 20% of medicines never even make it out of the packet.
Our protocol resulted in considerable reduced doses without any loss of diagnostic image quality, allowing a more accurate orthodontic diagnosis.
These results suggest that simvastatin can be developed as an important drug for the treatment of prostate cancer either alone or in combination with reduced doses of chemotherapeutic drugs such as docetaxel to improve the efficacy and reduce the side-effects.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com