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Patients with EDS IV have a mutation in the COL3A1 gene resulting in reduced amount of collagen III in their skin and other connective tissue such as the walls of the arteries and intestine.
The expected 4 bands of 1.1, 1.7, 3.2 and 4.0 kb were present in all of the genotypes though in reduced amount in OEX (see [ 17] for identification of the individual bands).
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Hydroxylamine was detected in reduced amounts possibly due to the unstable nature of hydroxylamine and rapid transformation to the next intermediate, nitrite [ 14].
Based on the comparison of observed responses, it is found that the addition of 1.5% of steel fibers is effective in reducing amount of steel rebars in the beam column joints of railway bridges.
Furthermore, our protocol also showed the superior efficacy in reducing amount and rate of blood transfusion, and maintaining the Hb level, over the control group.
These results suggested that the TtsfGFP could be successfully purified using Ni-NTA beads, although in a reduced amount.
Spectrin was present in normal amounts, in contrast to the reduced amount present in band 3 Coimbra (data not shown).
This modification results in only a slightly reduced amount of microporosity as determined using nitrogen adsorption.
As shown in Figure 2, HLA-B27 was detected in association with TAP, but in significantly reduced amounts compared with mutant KG-1.B27.H114D.D116Y.
All three GBPs showed an association with membranes, whereas their respective CaaX deletion mutants were either not detectable in the membranous fraction (GBP-1ΔCTIS and GBP-2 ΔCNIL) or were present in significantly reduced amounts GBP-5ΔCVLL GBP-5ΔCVLL
In addition, reduced amounts of mitochondrial DNA, destructed mitochondrial cristae, and inner/outer mitochondrial membrane structure are also directly linked to the increased incidence of AD.
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