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Preliminary results using similarly sized particles that were prepared with and without carbonate suggest a small decrease in reactivity with the inclusion of carbonate (reductive dissolution is only 1.3 times faster for the carbonate-free particles).
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The antigen reactivities marked in blue, in contrast, manifested an increase in their IgG reactivities during early tumor growth followed by a marked decrease in reactivity with the removal of the A9F1 tumor.
To compare the reactivity of this antibody with the reactivity of mAbs M2, M3 and M4, the anti-GAGE-7mAb was tested in parallel with M3 for reactivity with the panel of normal and cancer tissues by immunohistochemistry.
In SF and in anti-CCP2 IgG purified from SF, reactivity with the CEP-1 peptide was significantly stronger than reactivity with the other citrullinated peptides.
It showed no reactivity with the related ZPB protein in ELISA and Western blotting.
In our study, all normal liver tissues lacked reactivity with the CHO-131 mAb.
However, in some patients, particularly autoimmune hepatitis patients, citrulline-independent reactivity with the antigen may occur.
Therefore, we concluded that the spheroid inclusion-like reactivity with C4F6 was either some type of cross reactivity with the corpora amylacea deposits or some non-disease related association of SOD1 with these structures.
Chromophobe RCCs showed a weak reactivity with the antibody, while oncocytomas demonstrated no reactivity.
Regarding the chemical properties, both enantiomers solely differ in their reactivity with other chiral molecules.
In Hand-Foot-Mouth disease (HFMD) for example, extensive enterovirus and human microbiome cross-reactivity (and limited cross-reactivity with the human genome) seemingly predicts immunodominance.
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