We identified that PGF2α induces the expression of isoform 4 of RCAN1 (Fig. 4A) in rapid time-dependent manner, with maximal levels of expression after 4 h (Fig. 4B; P < 0.001).
When plasmid selection (-URA) was maintained throughout the experiment so that only plasmid retaining cells would survive, a rapid time dependent decrease in survival was observed.
AML exhibited rapid time dependent kinetics of bacterial killing.
Detection of the primary antibodies bound to surface-expressed receptors by FACS analysis revealed a rapid time dependent decrease of CXCR7 (Figure 4D).
There was a rapid time-dependent increase in mitochondrial superoxide generation in both cell lines, evident in H929 cells within 15 s of the addition of niclosamide and within 60 s in JJN3 cells.
In contrast, there was a rapid time-dependent linear increase of [F]FETA uptake by RIF-1 cells under nitrogen, which was 3.0- and 4.3-fold as compared to the normoxia values at 60 and 120 min p.i., respectively.
Retrospective doses may be more difficult to estimate because of the fairly rapid time-dependent loss of "stable" aberrations in blood lymphocytes.
Madar et al. showed rapid time-dependent accumulation of F-FBnTP in mongrel dog cardiac myocytes and prolonged retention [ 57].
In vitro RFP expressing B16F10 tumor cell (RFP/B16F10) culture system, the siRNA GC PEI NPs presented a rapid time-dependent cellular uptake profile within 1 h.
RO5126766 inhibition resulted in a rapid time - and dose - dependent decline in [18 F]FDG uptake in both mutant xenografts.
Another inhalation study reported that C57BL/6J mice exposed to MWCNTs aerosol (10 mg/m, 5 h/day) for 2, 4, 8, or 12 days showed pulmonary inflammation and damage with rapid development of pulmonary fibrosis in time dependent manner [ 24].
