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Whether reducing the resting heart rate can have a favorable effect on cardiac function needs to be investigated further in prospective intervention studies using heart rate-lowering drugs.
On the basis of our results, we can derive two hypotheses that have not yet been tested in prospective intervention studies.
While there is growing evidence around the validity and reliability of this approach for sub classification [ 12– 14], there remains little evidence of its clinical effectiveness in prospective intervention studies.
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Analysing recent results in detail may contribute to improving trial design and analysis, expediting the translation of a novel agent's potential benefit, assessed in prospective interventions, to clinical practice.
On this basis, women homogenous for age, parity, education and exposure to risk factors could be enrolled in parallel in the prospective intervention and in the observational comparison arm.
In this prospective, intervention and response study, 30° PLR of both legs was performed in 20 supine patients receiving mechanical ventilation after elective cardiothoracic surgery.
In this prospective intervention study, the proportion of patients with ≥ 1 medication transfer error (MTE) at ICU admission was reduced from 45.1 to 14.6% and at discharge from 73.9 to 41.2%.
In this prospective intervention study, 33 obese patients with obstructive sleep apnoea syndrome (OSAS) (24 men, 9 women) were consecutively enrolled for a weight reduction program at the Obesity Unit, Karolinska University Hospital.
Thirty-six people with gout participated in a prospective intervention study over 8 weeks.
In the prospective intervention group patients will undergo rTKA using CAS.
The included patients were also taking part in a prospective intervention study aiming to reduce hospital readmissions.
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