In each region, there was a rise in proportion tested with increasing age for age groups up to 74 years.
Accuracy was analysed using a two-group difference in proportion test to detect any difference between the two feedback conditions.
A difference in proportion test was applied to the prevalence of TTN truncations in senior athletes vs. literature controls, as well as the fraction of TTN truncations that map to the Novex-3 exon.
Including all the adverse events, the difference-in-proportions test was significant (p = 0.005) between the two groups.
We used excel to calculate unadjusted chisquare tests for the overall differences in proportions (test for homogeneity).
First, preference for home-based testing compared to facility-based alternatives, as demonstrated in studies done in Africa – although in the context of smaller research studies – and second, wherever home-based VCT has been tried it has generated a massive increase in proportions tested in comparison to more traditional clinic-based VCT.
Since tests based on a discretization of the gene-level test statistics, e.g., Pearson's difference in proportions test [ 31], are simply a special case of the unadjusted mean difference statistic, S D, the PCGSE method using the unadjusted t-test can be used as a proxy for existing contingency table methods in both the simulation and real data examples.
First, the PN/PS was significantly lower in codRNAs than in lncRNAs (proportion test, p < 10−5), denoting stronger purifying selection in the former.
Furthermore, the percentage of CNVs is statistically higher in XLMR than in controls (proportion test Z = 2,51, p = 0,012; Fisher's exact test: P-Value = 0,035).
There was a steady increase in the proportion tested across all health districts in the region, more prominent in non-urban districts.
To test whether the apparent enrichment of antisense genes and pseudogenes is statistically significant, the built-in binomial proportions test prop.test in R was used.
