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We recently defined that the loss of effective immunity relates to the retardation in proper functioning of a highly complex network of hundreds of thousands of molecular signals between the biphasic response profiles of 2 biologically opposing arms, Yin (tumoricidal) and Yang (tumorigenic) properties of self terminating mechanisms of acute inflammation [6, 7].
Selenium also plays a key role in proper functioning of the glutathione peroxidase system, which has been linked to depression.
As DUBs are integral regulatory molecules of most of the cellular functions, it has high implications in proper functioning of the cellular machineries (elaborated in other reviews [ 20, 21, 23, 24, 93– 93]).
These are very beneficial in lowering the bad cholesterol level as they help in proper functioning of liver.
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Its involvement in proper function of cardiovascular system, efficient neovascularization of ischemic tissues or progression of tumors is relatively well known [24].
These mutations implicate a role for the mitochondria in proper function of the ovaries.
In addition, proper functioning of liver in HCC patients is often complicated by cirrhosis, adding another layer of complexity which cannot be replicated in a subcutaneous model.
There's an overwhelming public interest in the proper functioning of the extradition arrangements in the US.
The large number and proportion of members of the Clostridiales order are indicative of the important role of these bacteria in the proper functioning of the microbial community in an anaerobic digester fed with complex substrates.
The integrated disease surveillance and response (IDSR) strategy was adopted in Ghana over a decade ago, yet gaps still remain in its proper functioning.
As Dscam1 is also critical during the launch of innate immune responses in insects, self-binding may also play a role in the proper functioning of the immune system.
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