However, not all of the QTLs detected in previous bi-parental populations were detected in our association panels.
The average PIC (0.30) and Gene diversity (0.33) values observed in this panel of accessions are comparable with the results in previous studies using bi-allelic markers.
It is likely that the high volume of distribution (>3000 l) and long t1/2 (135 h) of volasertib resulted in an increased and more sustainable tumour exposure than in previous studies with BI 2536, a dihydropteridinone derivative similar to volasertib.
Specifically we compared a three-factor model reported in previous studies, with a proposed bi-factor model [40].
The aims of the present study were to assess the psychometric properties of the Stagnation Scale in a sample of MOH patients, and to compare two factor models: a three-factor model reported in previous studies and a proposed bi-factor model.
In previous work, we observed a bi-phasic increase in the number and relative percentage of activated monocytes with the second peak occurring with peripheral immune system dysfunction and a steep decline in NAA/Cr ratios [33].
The reproducibility of BI-RADS has in previous papers demonstrated moderate to substantial agreement [ 23- 25, 28].
In previous work in our laboratory, we biosynthesized the bis-type of bioreductive aziridinylnaphthoquinone series compounds and evaluated their anti-cancer activity [ 16, 17].
Instead of adopting the single-objective formulation established in previous research, we propose to formulate CWLP as a bi-objective optimization problem.
