Acute effects include intoxication, impaired cognition and motor function, elevated heart rate, anxiety, and psychosis in predisposed individuals.
Theoretically, shift work may result in a circadian misalignment that could trigger CH in predisposed individuals.
In predisposed genetic individuals the intestinal inflammation can caused a variety of metabolic, neuroendocrine, neurological complications and hormonal perturbations.
Catecholamines also activate brown fat with beta-blockers having been advocated as an intervention to reduce this confounding finding on FDG PET in predisposed individuals [22].
Prevention of headache chronification in migraine patients would thus appear crucial also for preventing the development of fibromyalgia in predisposed individuals or its worsening in co-morbid patients.
The seeds of the peanut plant Arachis hypogaea contain an array of allergens that are able to induce the production of specific IgE antibodies in predisposed individuals.
It is possible that the activation of peripheral nociceptive stimuli through trigger points may lead to the activation of trigeminovascular system, via nucleus caudalis, in predisposed individuals, determining a migraine attack [42].
Rarely, severe life-threatening reactions may occur in predisposed individuals, such as patients with asthma.
Under inflammatory conditions, PL directly binds to its cell surface receptor, annexin II, which is expressed on activated monocytes/macrophages, DCs and keratinocytes, a critical initiating step in the pathogenesis of psoriasis in predisposed individuals.
Common variants of MTNR1B, G6PC2 and GCK are associated with elevated FPG and impaired insulin secretion, both individually and jointly, suggesting that these risk alleles may precipitate or perpetuate hyperglycemia in predisposed individuals.
This would correspond with psychodynamic and cognitive reasoning of delusional creation in predisposed individuals.
