Suggestions(1)
Exact(2)
The presence of Ser (S) in place of the consensus N6 in the second TPR motif of AtPhox1 and AtPhox4 (Table 2) warrants investigation of this substitution in the context of Hsp90/Hsp70 binding.
Twelve of the 13 substrate-contacting residues are fully conserved in all of the putative PurO protein sequences, while residue 54 is conserved in 23 of 25 sequences, with the two Methanocellales having a serine in place of the consensus asparagine.
Similar(58)
That is, in the regions where reads mapped, the resulting consensus sequence was inserted in place of the corresponding region in the Los Alamos reference genome.
" in place of the date.
Upon closer inspection, it appears that that the second Zn2+-binding region in RING0 adopts a similar fold as the HOIL-1 NZF domain (RMSD=1.7 Å) using valine/glutamine residues in place of tryptophan/asparagine in the consensus and having a two-residue insertion within the second zinc-co-ordinating pair of cysteines.
When the heterogeneity among genes is due to reticulate evolution, phylogenetic networks should be used in place of traditional or consensus phylogenetic trees [ 3- 5].
In place of biochemistry, the D.S.M. offers expert consensus about which clusters of symptoms constitute particular mental illnesses, and about which mental illnesses are real, or at least real enough to warrant a name and a place in the medical lexicon.
And in place of management by committee and consensus, Mr Löscher gave each of his sectoral heads full responsibility for their businesses.
But we can predict that without a ranked voting system like IRV in place, the true consensus choice of Virginia's Democratic voters will likely remain a mystery long after the polls have closed.
A very telling example of compensatory mutations is provided by the mutations K6N+F11V+P20L (i.e. mutations 1, 3 and 4 placed in the context of the consensus sequence).
In 1998, a WHO consensus conference defined urothelial cancers and the preferred synomyn, urothelial cell carcinoma (UCC), in place of transitional cell carcinoma (TCC) (Epstein et al, 1998).
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Justyna Jupowicz-Kozak
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