Sentence examples for in physiological settings from inspiring English sources

However, cell adhesion molecules rarely work alone in physiological settings.

However, it is still unclear whether miR-34a directly controls Wnt signalling in physiological settings and how this interplay affects the biology of the mammary gland.

The understanding of IL-12 regulation in physiological settings will undoubtedly lend valuable support to the design of therapeutic applications of IL-12.

Although this dual function model is well demonstrated at the molecular level, few studies have addressed the presence or the role of unliganded TR-induced repression in physiological settings.

These data thus provide in vivo evidence for the presence and a role of unliganded TR-induced gene repression in physiological settings and strongly support our earlier model that unliganded TR represses T3-response genes in premetamorphic tadpoles to regulate the progress of development.

Studying the invasion of cells into cell-free ECM hydrogels is not an accurate model, because in physiological settings, all tissues usually contain a non-zero concentration of cells (e.g. stroma cells) [43], [44].

Clearly, further studies investigating the role of the coagulation cascade factors in more physiological settings, and in particular their potential ability to affect normal tissue stem cells under extreme growth stimuli, are warranted.

We later showed that it plays a role in many physiological settings; for example, in wound repair.

Caspase-3 is a critical factor in determining cell death phenotypes in many physiological settings.

In addition to the above mentioned work by the Ullrich group [ 46], further studies demonstrating the ability of thrombin and its precursor enzyme, prothrombin, to induce EGFR activation [ 46, 86- 88] points to the participation of PARs in this "RTK transactivation" pathway in many physiological settings.

In this review, we provide a comprehensive overview of the existing Tg and KO mouse models generated by targeting many individual components of the SCF E3 ligases, and discuss their biological functions under in vivo physiological settings, which are summarized in Figures 3, 4, 5.