Sentence examples for in perp from inspiring English sources

In liver, malondialdehyde (MDA) production was decreased by 30% in PERP supplemented rats, especially with RO and CI (−34%, P<0.05).

Finally, the weakest previous support was for rs6922466 in PERP.

Decreased c-myc in MCF10A also agrees with an increase in PERP as c-myc protein represses expression of PERP [ 41].

Instead of widespread loss of Perp throughout the entire mammary epithelium, K14-Cre expression resulted in Perp deletion in only a subset of individual cells in a rather stochastic fashion, as reported [ 37, 38] and recapitulating the way in which gene mutations typically occur in cancer [ 39].

Instead, detectives came and went, rushing out to make arrests and dragging in perps.

Weak matching rules for a quasicrystalline tiling are local rules that ensure that fluctuations in "perp-space" are uniformly bounded.

The staining is specific for Perp because it can be blocked with a Perp peptide and is absent in Perp-/ mammary gland.

The disrupted mammary epithelial homeostasis and enhanced recruitment of inflammatory cells in Perp-deficient epithelia we observed here and previously [ 17] represent intriguing phenotypes because chronic inflammation is known to contribute to cancer development and progression [ 35].

Despite decreases in desmosome components in Perp-/ mammary epithelial cells, we found that Perp-/ transplanted epithelium underwent grossly normal morphogenesis through distinct developmental stages, similar to wild-type transplants.

These findings suggest that Perp deficiency is associated with enhanced inflammation around the mammary epithelium in the context of this transplant assay, reminiscent of the increase in inflammatory cells we observed in Perp-deficient skin after prolonged UVB exposure [ 17].

Given the previously reported experiments showing that desmosome-mediated adhesion contributes to proper mammary epithelial morphogenesis and organization in culture [ 9], we examined whether the reduction in desmosomal constituents we observed in Perp-/ mammary epithelial cells would translate to defects in mammary gland development.