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Future work should be done to pinpoint the differences in pathways that cause miR-155 to be an EMT suppressor in cervical cancer but an EMT activator in endometrial cancer.
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Newly proposed differences in genetic pathways that cause cancer in humans and mice invigorated the ongoing discussion about the legitimacy of the murine system to model the human disease.
Second, the positioning of uric acid and xantine oxidase in pathophysiologic pathways that cause CV events in GA and hyperuricaemia.
These data suggest that if similar neuronal damage could be produced in the developing human brain, it could account for the qualitative or quantitative defects in neuronal pathways that cause a major handicap in brain function following prenatal exposure to cocaine.
These genes encode proteins involved in several biochemical pathways that cause cell shrinkage, condensation of chromatin, damage to cell membranes and nuclear fragmentation.
Despite significant improvement over conventional static mapping, functional mapping has still a major limitation in characterizing developmental pathways that cause a final phenotype and unraveling the underlying genetic mechanisms for trait formation and progression.
Since there is no known experimental treatment to induce unstacking of Golgi cisternae in interphase cells, we exploited normal pathways that cause unstacking in mitosis.
A variation on the molecule targets the proteasomes in immune cells (which differ from those in normal cells), disrupting biochemical pathways that cause autoimmune disorders.
The increasing likelihood is that we're going to be able to discover, in a systematic way, the underlying molecular pathways that cause these diseases.
There is some overlap between the physiological pathways that cause these alterations in PK.
Thus, potential stress pathways that cause neurodegeneration specifically in the TDP-43 model can be identified more precisely.
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CEO of Professional Science Editing for Scientists @ prosciediting.com