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This may be due, in part, to variability in study design and sampling methodology across studies.
Conflicting results have been found with onabotulinumtoxinA which may be attributed, at least in part, to variability of doses, study protocols, inoculation sites and headache frequency of enrolled patients.
Regardless, these data demonstrate that BCO allele-specific sequences interfere with tag-antitag recognition, indicating minor variant detection with the multiplex OLA was hampered by impaired BCO binding and assay variability was due in part to variability in BCO binding (BCO mimic Bmax coefficient of variation = 0.33 for the data set).
Notably, for cytobrush samples, the concentration of RC-101 was directly proportional to the amount of protein within a given sample (data not shown), suggesting that the differences observed between samples may be attributed in part to variability in the number of cells retrieved by brushing.
However, this was due in part to variability across trials.
This may be due, at least in part, to variability in the study size, immune and disease status of study participants (CD4+ cell counts and viral load), receipt and type of HAART, pneumococcal immunization history and the particular endpoint(s) assessed.
Similar(54)
Some sequences are particularly variable in specific structures (ASL exhibited variation of 28% in the cerebral white matter) or in thin structures (quantitative T2 varied by up to 73% in the caudate) due, in large part, to variability in automated ROI placement.
In summary, the currently available results from studies of transcriptomics show a variability that must be due at least in part to the variability of the platform used and the methodology for data analysis and interpretation.
However, many studies have found it difficult to reproduce these results [ 8– 10] due in part to metabolic variability [ 11].
The absence of a clear main effect or interaction may be due, in part, to substantial variability in context similarity effects during delayed recollection.
This difference in phenotypic expression of proteotoxic mutations is proposed to be due, at least in part, to the variability in genetic background.
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