Our data indicate that in parallel with the predicted activation of immune response and tissue injury pathways, there is simultaneous activation of pathways for counter regulatory and protective mechanisms that would balance and limit the ongoing inflammatory/immune responses.
This trend occurred in parallel with increasing age and predicted surgical risk at referral.
In parallel with Moore's Law, which predicts that the number of transistors on a chip increases exponentially, the clock speed has done the same, doubling roughly every 18 months from thousands of ticks per second in 1971, to millions in the 1980s, to billions today.
The inverse of these IC50 values (1/IC50) is plotted in parallel with the top 20% of predicted binding peptides for MetaSVMp.
Prediction of the likely effect of the detected polymorphisms in the encoded protein was carried out with SnpEff v.4.0 [ 65], and effects of single amino acid substitutions on protein function were predicted in parallel with SNAP [ 66] and PROVEAN [ 67] utilities.
In this regard, we believe that the evaluation of insulin signaling pathway through PI3K/Akt in liver, muscle and adipose tissue may be important indicators of this over-reaction at the tissue level, and the improvement in this signaling pathway, induced by some treatments, in parallel with a decrease in tissue inflammation, may predict the effectiveness of this treatment.
In this regard, we believe that the evaluation of insulin signaling pathways through PI3K/Akt in liver, muscle, and adipose tissue may be important indicators of this overreaction at the tissue level, and the improvement in this signaling pathway, induced by some treatments, in parallel with a decrease in tissue inflammation, may predict the effectiveness of this treatment.
In parallel, all predicted ORFs with an N-terminal secretion signal and transcriptional evidence were taken as candidate regions and manually annotated.
Thus (as predicted by [10]), H3N2 charge increases in parallel with net antigenic escape, at least over the early part of the virus's history in humans.
We have, however, shown that expression of hsa-miR-92a and hsa-miR-92b are increased following cardiac rehabilitation, which occurs in parallel with a confirmed reduction in expression of two of their predicted target genes.
These measures can be used in parallel with the traditional definition of the Capital Asset Pricing Model (CAPM) beta to better predict the time-varying systematic risk of an asset.
