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Blocking of Shh signalling led to a sharp decrease in the number of perpendicular divisions and a corresponding increase in parallel divisions.
The increase in parallel divisions at later ages observed in the current study correlates with the period of decrease in GNP proliferation during later development.
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Interestingly, in Cyclopamine treated animals, there was a dramatic increase in the percentage of parallel divisions (71%), when compared to control (56%).
Briefly, the immunofluorescence quantification was performed using the formula: where L and R denote proximal and distal positions respectively in a parallel division and as left and right cell respectively in perpendicular division, to get the normalized ratio for PH3 and β-Catenin.
In the SAG treated animals, the percentage of parallel divisions was significantly reduced (46%) (Fig. 2R).
In Drosophila embryos, Insc acts as a switch to drive cells toward vertical divisions, whereas cells with inactive Insc drive parallel divisions [ 37].
This debate within the left also parallels divisions evident in earlier wars.
Viral genomes are primarily present as nuclear episomes, which replicate in parallel to cell division.
Thus, viral genomes are primarily present as nuclear episomes, which replicate in parallel to cell division.
As symmetric stem cell division produces two daughter stem cells (subsection "Gravin contributes to spindle orientation of germline stem cells during spermatogenesis"), defects in parallel symmetric cell division would lead to detachment of one daughter cell from the basal membrane and an expected decrease in stem cell population.
In 1999, Parliament established a Western Regional Gun Court with its own Resident Magistrate's, High Court, and Circuit Court divisions, in parallel with the jurisdictions and powers of the central Gun Court divisions.
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