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We observed that, although TAD borders were conserved during EMT transformation (with 50% of all borders conserved over the three time points), they increased in overall strength with longer treatment, indicative of more stable borders and increased intra-TAD interactions (Fig. 4c, left panel); this may reflect novel and biologically relevant chromatin interactions within TADs36,41.
A new understanding of degradation has been obtained and changes in overall strength and colour can be described for the first time in chemical terms.
One interpretation is that, over time, recovery results in resting connectivity that is diminished in overall strength and increased small-worldness approximating what is observed in healthy adults.
Treatment results in reduced pathology, better muscle physiology leading to an increase in overall strength, and an ability to resist fatigue after forced exercise; a surrogate for the six minute walk test currently recommended as the pivotal outcome measure in human trials for DMD.
This causes variation in overall strength of the serum.
Similar(55)
Larger variation in the distribution of interfacial bond strengths was found to result in a decrease in the overall strength for PCD grades.
Differences in the overall strength of the decay in fluorescence intensity indicate slightly different binding geometry for the four GAGs.
"He was a big believer in the overall strength of artists as a community".
The net result is a reduction in the overall strength of the engineered enzyme's electrostatic potential field, and it appears that the specific nature of this remodeled field underlies the variant's reduced susceptibility to inhibition by anionic biopolymers.
Unlike firing rate, however, PGC results for the "incoming" sink relationship indicated that this increase was also associated with a decrease in the overall strength of connections coming into the area near the tetanic site and an increase in some areas outside this region.
Branch-site models assume a very specific form of functional divergence that is, a punctuated burst of adaptive sequence turnover but functional divergence can instead manifest as variation in the overall strength of constraint or residue conservation between clades [ 99].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com