A risk estimate for all cancers other than breast in female relatives was not made in this study, but our recalculation on the basis of data reported in the paper indicates that the risk was much lower than that of male relatives.
After our recalculation, the estimates become closer also for Canada, Japan, Switzerland, UK, Mexico, and Malaysia.
We were not able to identify the reasons for such erroneous calculations, particularly the frequency of reported calculations that were greater than our recalculation.
Our recalculation of the HVI from census tracts to ZIP codes could have slightly changed the relationships observed, had health data been available at the census tract level.
In addition, we found that exacerbation outcomes, particularly for severe exacerbations, were reported in several ways (number of exacerbations, number of patients with at least one exacerbation, and weighted or non-weighted exacerbation rates (annually or in other time frames)), underscoring the value of our recalculations to reliably compare strategies.
In our study, transforming the hop distance scores enabled a recalculation of the hop index without concern for the differences in the hop distances achieved on the ACLD patient's non-injured limb.
Similarly, in our probabilistic analysis, we found that 100% of model recalculations were consistent with the base case conclusion.
Our own recalculation of the available data fails to demonstrate statistically significant differences.
In order to assess inter-rater reliability regarding eligibility, we calculated the Phi statistic, which provides a measure of inter-observer agreement independent of chance [ 15] We calculated the hazard ratio (HR) and appropriate 95% confidence intervals (CIs) of PFS according to the HR reported in the original studies, communication with the authors, or through our own recalculations.
Some of the radiopharmaceuticals published in ICRP publication 53 [13] are included in the recalculation from effective dose equivalent [2] to effective dose in ICRP publication 80 [14] or have been completely modified in the later ICRP publication 106 [15].
