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A limitation of the present study is that our study group is very small with 11 infants and we therefore could miss some more differences in our parameters.
Considering a certain level of stringency in our parameters we still have found AS evidence in 44.6 % of intron-containing genes, slightly more than the 30 % recently reported [ 37].
The isotopic labelling strategy employed here is limited to triplexing so to enable a comparison of the protein expression profile for one colony to all others we employed a design similar to what we have done previously that maximized the statistical power of the experiment to detect effects in our parameters of interest [ 27].
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Hence, we decrease the probing rate in STP phase (r1 is set to be 1% in our parameter setting).
In our parameter setting, prices are somewhat more sensitive to excess supply and taxation than wages, resulting in stronger adjustment and initial real wage decreases.
In our parameter space analyses, SVR always strongly affected decay times but also rise times.
To explore the effect of uncertainty in our parameter estimates, we performed extensive one-way, two-way, and multi-way sensitivity analysis.
In our parameter space, the attenuation in brightness ranges in between 0 and 60%.
Variation in our parameter estimates was assessed by a bootstrapping procedure.
This prevents the introduction of additional biases in our parameter estimates.
Additionally, to account for uncertainty in our parameter estimates, we performed tests on the collected output of our MCMC method.
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