In order to inhibit autophagy, a psiRNA-hBeclin-1 Kit was used according to the manufacture's protocol (InvivoGen, San Diego, CA, USA).
Of particular note are S100ββ p53 and sirtuin p53 complexes, which demonstrate that this same p53 fragment is able to stably bind as both an α-helix and a β-sheet, respectively, and has achieved this in order to inhibit apoptosis in a similar fashion in both.
In order to inhibit the cancerous cells, RNase A must enter cells and mount to a certain concentration.
A suitable light-emitting device for OCT applications is the superluminescent diode (SLD) which combines many aspects of the laser diode but requires a range of techniques to be employed in order to inhibit lasing and ensure a broad emission bandwidth [6].
The tethering of γ-Fe2O3 nanoparticles on the surface of MWCNT was achieved by a modified sol gel reaction, where sodium dodecylbenzene sulfonate (NaDDBS) was used in order to inhibit the formation of a 3D iron oxide gel.
In order to inhibit apoptosis, Bcl2 forms a heterodimer with Bax [28].
Therefore, we pretreated the cells with 20 μM selegiline in order to inhibit both isoforms of MAO (A and B) in neurons and astrocytes.
Encouraging pre-clinical studies demonstrated the benefit of adding bevacizumab to trastuzumab, as compared with treatment with trastuzumab alone, in order to inhibit tumor growth further in a breast cancer xenograft model [ 40].
In order to inhibit SUV39H1, cells were treated with a 10 nM final concentration of chaetocin, which is a specific inhibitor of SUV39H1 [ 35].
This integrin-mediated event is dependent upon direct binding between the β6 integrin subunit and extracellular signal-regulated kinase 2. Targetting either β6 or its interaction with extracellular signal-regulated kinase in order to inhibit matrix metalloproteinase activity may offer a useful therapeutic approach in preventing growth and spread of colon cancer.
