Sentence examples for in optimum context from inspiring English sources

DOI: http://dx.doi.org/10.7554/eLife.07939.016 The E144R mutation conferred a greater increase in leaky scanning of GCN4 uAUG-1 in optimum context (∼20-fold) vs uAUG-1 in poor context (∼fourfold).

We agree with his/her interpretation and had actually laid the groundwork for advancing it as a likely scenario with the text in the second and third paragraphs of the Discussion that seeks to explain the increased leaky scanning observed for uAUG-1 in optimum context as the result of el.uORF1 being unstructured.

This conclusion would be consistent with the fact that E144R and R225K also suppress recognition of the UUG start codon of his4-301 mRNA, which resides in moderately strong context, as near-cognate codons are inherently weaker initiation sites even when present in optimum context.

Remarkably, rps5-E144R confers a dramatic increase in leaky scanning through el.uORF1, elevating GCN4-lacZ expression by 20-fold for the construct containing optimum context (−3AAA−1) at uAUG-1.

The realization that AIDS programs have sometimes, in their single-minded zeal for results in less than optimum contexts, been misinformed and poorly planned should be taken as constructive criticism, instead of eliciting defensive responses.

And, the theory goes, we need both to come into balance to stay in optimum condition.

Religion is supposed to be about losing your ego, not preserving it eternally in optimum conditions.

I'm not listening in optimum conditions all the time.

Immobilization of MnP enhanced optimum temperature but caused acidic shift in optimum pH of the enzyme.

In this context, an optimum sizing methodology is currently developed, based on the criterion of minimum embodied energy.

In this context, the optimal temperatures of the working fluids, the optimum performance coefficient, the optimum specific cooling load and the optimal distribution of the heat exchanger areas are determined in terms of technical and economical parameters.