Exact(3)
In one large scale study, when compared to compliant patients, those who skipped one or more hemodialysis sessions in a month had 5.7% greater interdialytic weight gain and higher serum phosphate levels.
Such dual-faced biological functions have been discovered in many miRNAs, such as miR-503-5p miR-503-5p miR-503-5psregulation of miR-490-3p in CRC has been found in one large scale screening yet [ 18], therefore, it's worthy of further investigandon to unvetc its roles in CRC.
Nevertheless, it is worth underlining the fact that at least in one large scale study a negative evolution of the results over time, following a first period of clinical improvement, was hypothetically related to the event of an otherwise undetermined immune response [14].
Similar(56)
Interestingly, such a profile occurred in only 2% of patients in one large-scale study based on 3000 breast cancer cases [ 22], while in our STS study this profile was seen in 13% of tumors.
Thus, on the basis of a prospectively defined subset of trauma patients in one large-scale clinical trial of albumin versus crystalloid resuscitation [ 4], the former was associated with an increased risk for death.
In one large-scale investigation, for example, three-year-old children who had attended child care centers that met nationally-recommended guidelines for structural quality had more advanced cognitive and social development than those attending lower quality centers (NICHD Early Child Care Research Network, 1998).
The complexity of the human proteome exceeds that of the transcriptome, with more than 290,000 unique human peptides having been identified in one large-scale effort [ 16].
Even low-dose ibuprofen (400 mg/day) was found to be significantly more efficacious than high-dose acetaminophen in one large-scale trial [ 50].
In one large-scale 5' RACE experiment, only 57% of clones generated sequences that were sufficiently long and unambiguous to be identified by alignment with a gene transcript [ 9].
In one large-scale study of the yeast proteome, a third of proteins were annotated with multiple locations, which demonstrates that this is not a problem confined to 'special case' proteins (Chen et al., 2007; Huh et al., 2003).
For example, the interaction between SHP [NR0B2] and RAR-gamma [NR1B3] is found only in one large-scale Y2H experiment [ 26] ; nevertheless, there is at least one interaction of level 1 between the NR0B and NR1B phylogenetic groups (SHP [NR0B2] – RAR-alpha [NR1B1]).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com