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The measured TR95 and those calculated with model (2) are in observed to be in good agreement.
Within the subgroup, an almost four-fold variation in observed to expected mastectomy rate ratio between breast units is demonstrated (range 0.55 1.95).
Two-fold variation in observed to expected unit mastectomy rate coefficient is demonstrated overall (range 0.66 1.36), increasing to almost four-fold variation in cancers less than 15 mm diameter (range 0.55 1.95).
Within the subgroup with small tumours (total tumour size less than 15 mm diameter), there is an almost four-fold variation in observed to expected coefficients following case-mix adjustment.
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Provided richer data, geographically-weighted regression offers an interesting alternative method to identify spatial discrepancies in observed-to-expected ratios [ 27].
Furthermore, the presence of N-linked glycosylation was experimentally confirmed by treatment with N-glycosidase F leading to a fall in observed MW to 35 45 kDa (Figure 3b).
One might argue that higher levels of autocorrelation in observed compared to simulated data reflected a sampling artefact due to the accumulation of many small samples over a long period [34].
Conditioning on the propensity-score results in unbiased estimation of the expected difference in observed responses to two treatments.
Its role in observed tolerance to quinolones and fluoroquinolones in isolates carrying the gene is equivocal as this gene typically mediates only low level resistance to these antimicrobials.
Bronchopneumonia due to Bordetella bronchiseptica infection was confirmed in a squirrel that was observed to die in respiratory distress.
In total, the excess ratio of observed to predicted in situ and invasive cases was 36.2%.
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