Sentence examples for in numerous models from inspiring English sources

SERCA2a activation is tolerated in healthy animal models and significantly enhances cardiac function in numerous models of heart disease14,15.

Denitrification is simulated in numerous models, however most models do not take into account the denitrification occurring in shallow aquifers or the influence of recharge surface water in the alluvial aquifer with organic carbon and bacteria to activate denitrification.

MnTBAP is often referred to as an SOD mimic in numerous models of oxidative stress.

Like its predecessors the CLR retained elements of Mercedes-Benz's production cars, including a V8 engine loosely based on a design used in numerous models as well as bodywork based on the CLK and CL-Classes.

The variable role of Treg in the induction and maintenance of allograft tolerance has been described in numerous models.

Conversely, alternative macrophage activation state might be responsible for beneficial effects of PPAR-γ ligands in numerous models of ischemia [38], [42] [44].

The drug metabolist can determine the propensity of a novel chemical entity to either accumulate in the hepatocyte or undergo bioactivation in numerous model systems, from expressed enzymes, genetically engineered cells to whole animals.

The targeted introduction of mutations utilizing sequence specific transcription activator-like effector nucleases (TALENs) and the clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated (Cas) 9 system (RNA-guided nucleases, RGNs) has revolutionized reverse genetic approaches in numerous model organisms.

The DNA damage-dependent phosphorylation of Chk1 has proven to be an adequate indication of checkpoint activation and is well-recognized in numerous model systems [37], [38].

Conflicting results in numerous model systems in identifying the specificity of the antigen during suppression have made it difficult to identify precise parameters and mechanisms of Treg-mediated suppression [15].

NeuroD in the pancreas is a marker of endocrine progenitors in numerous model species, including zebrafish.