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Rats raised in small size litters showed similar IPGTT responses as those raised in normal size litters within the same maternal group (Fig. 3A,B).
Mice at 4 months of age were placed into large enrichment cages (EE, 6 8 animals per cage with a floor surface of 1875 cm2) or standard housed in normal size cages (6 animals per cage with a floor surface of 500 cm2).
Eleven of the 23 patients with positive nodes had metastases in normal size nodes (<8 mm).
Positron emission tomography (PET) using [F]fluorodeoxyglucose (F-FDG-PET) can demonstrate increased glucose metabolism in normal size lymph nodes.
Preliminary results suggest an improved accuracy in the detection of metastasis in normal size nodes using a lymph node-specific MR contrast agent[ 48].
Uptake of FDG is dependent on metabolic activity, not size of nodes, and FDG-PET will therefore identify tumour in normal size lymph nodes.
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Be aware that there is an overlap in normal sizes between male and female, so this can give you a hint, but it is not a foolproof way of sexing a turtle.
This was due to the detection of metastases in normal-size nodes.
Twenty-four hours after intravenous injection of USPIO, normal lymph node and malignant tissue have different signal intensities on MR images, thus this non-invasive technique may result in the detection of metastatic deposits in normal-size nodes[ 71].
Despite its high resolution and excellent depiction of anatomy, CT is limited by its inability to detect small-volume metastatic involvement in normal-size lymph nodes and to determine whether enlarged nodes represent metastasis or reactive hyperplasia.
The expression of other bHLH genes such as Nhlh1 and Nhlh2 may rescue some common neurosensory precursors in the utricle and saccule resulting in near normal size growth.
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