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In normal process, arsenate that enters the cell will be reduced to arsenite by ArsC gene before it is transported out of the cell by ArsB gene [ 10, 64].
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MMP have important roles in normal processes including development, wound healing, mammary gland, and uterine involution, but are also involved in angiogenesis, tumor growth, and metastasis.
Here we review recent studies linking epigenetic mechanisms to epithelial-to-mesenchymal transition as defined in normal processes, as well as abnormal transitions that lead to oncogensis.
These enzymes play an important role in normal processes of growth, differentiation and repair.
Matrix metalloproteinases are enzymes that cleave the extracellular matrix in normal processes such as morphogenesis, angiogenesis and tissue repair.
As both p38 MAPK and PI3K are involved in normal processes, inhibition of these signaling pathways may produce untoward effects.
Transcription factors play a central role in maintaining or modifying cell fate, either in normal processes such as development and cell differentiation, or in cancer.
Then, the Arabidopsis CPKs within Group IV of CPKs might play a role in normal processes during root growth and development.
Matrix metalloproteinase candidate targets and antitargets must be fully validated and their biological roles in normal processes, host protection, and cancer must be clarified.
Apoptosis is a physiological form of cell death important in normal processes such as morphogenesis and the functioning of the immune system.
Given the multiple roles of RTKs in coordinating basic biological processes, modulating their activation levels is a means of achieving different cellular responses in normal processes and in pathological conditions.
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