There are also policies and instruments such as the Stability and Growth Pact, that are factors in non-implementation.
While these analyses cannot demonstrate that the effect of SRTS safety improvements extends beyond the geographic areas to which they are targeted or that there was a more comprehensive benefit, the overall state average may actually obscure more dramatic improvements in the implementation areas than in the non-implementation areas.
Apart from risk and ethics frames we also find an economic frame, emphasising the opportunities for future benefits or, alternatively, the possible losses in case of non-implementation.
We subsequently examine the computational bottlenecks present in non-SSE implementations with a profiling analysis.
Previous research reporting socioeconomic inequalities in use of adjuvant therapy for cancer suggests that non-implementation equates to non-uptake of care for cancer patients.
We also collapsed the 5 IMD quintiles to two groups (IMD1-3 and IMD 4 5), and found that reasons for non-implementation were similar, although patient death was a more frequent reason for non-implementation in the least deprived group (data not shown).
No single study, including the famous Modification of Diet in Renal Disease, was conclusive and even if systematic reviews are in favour of protein restriction, at least in non-diabetic adults, implementation is lagging.
Reasons for unsuccessful or non-implementation of guidelines in clinical practice are now being recognized beyond the lack of knowledge, including (lack of) comprehensiveness, relevance, simplicity, applicability and presence of (negative) role models [14].
39 However, non-implementation may result in care delays which might impact upon morbidity rather than mortality something that was not addressed in these cardiovascular models.
This was because, on the basis of our clinical experience, non-implementation is commonly not explicitly recorded in patients' records.
Although automatic differentiation is traditionally considered to slow for implementation in non-linear PDE and ODE solvers, it has recently been demonstrated [E.
