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Both instruments can identify accurately infants who are in need of further evaluation and/or rehabilitation interventions.
Albumin use was associated with improved oxygenation, diuresis and haemodynamics, and represents an approach in need of further evaluation.
A more biocompatible humanized alternative but still in need of further evaluation is the radiolabelled CD3 antibody 99mTc-SHNH-visilizumab.
Likewise, the reduction of platelet EGF levels may be a promising marker for AD-related changes and is in need of further evaluation.
In line with this advice, the cutoff on the DEPS-R is not diagnostic but rather a threshold to identify at-risk individuals in need of further evaluation.
While training and interventions to address neonatal and pediatric bereavement are common in U.S. hospitals, training programs or tested protocols for supporting parent bereavement after a stillbirth remain inconsistent and in need of further evaluation and development [ 17- 24].
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We conclude that, beyond smoking, factors such as positive RF and anti-CCP antibodies and ongoing corticosteroid treatment may, in combination with pulmonary symptoms, identify individuals in need of further pulmonary evaluation.
The BINS is used to monitor the course of an infant's development and identifies infants with developmental delays or neurological impairments who are in need of further diagnostic evaluation [ 21, 22].
Our results are in accordance with previous studies [ 5, 19, 21] that clearly showed the unsuitability of SDQ for diagnostic purposes in a clinical setting, but contrary to these studies our results call into question the usefulness of SDQ to identify children who are in need of further psychiatric evaluation, as PPV and LHR+ results are low.
The efficacy of skin treatment with NAE-8® before as well as after UV exposure is also in need of further ongoing clinical evaluation.
Mutations of PIK3CA have been identified in 33% of such tumors; hence, multiple phosphatidylinositol-3-kinase (PI3K /protein kinase B (PKB, also AKT /mammalian target of rapamycin (mTOR) inhibitors have been tested in preclinical studies, some of which resulted in the need for further evaluation in early-phase clinical trials [69].
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