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Because NCOs were detected using the SNP information for each spore in the chromosomal context, reduced SNP coverage in spore 4 likely caused a decrease in NCO detection, providing another possible explanation for under-estimation of the NCO number.
The presence of varicose veins in NCO limbs was similar at each interval.
Considering the distribution of SNPs in NCO tracts, we found lengths that vary over more than an order of magnitude, from hundreds to thousands of base pairs.
It is generally accepted that cryptorchid testes are more prone to develop neoplasia, although such defects also occur in NCO males (McEntee 1990; Mostafi 1977).
Although one recent sperm-typing study reported two recombination hotspots that exhibit GC-bias in NCO resolutions (Odenthal-Hesse et al., 2014), most of the evidence of gBGC in mammals is indirect.
This bias may be caused by a lower coverage of the telomeres in the low density SNP array, and makes the analysis of potential differences in NCO rate between the sexes difficult.
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Furthermore, we provide an in-depth experimental study of the Na storage reaction (sodiation and desodiation) in NCO-NNA.
According to the XPS results, the electron couples of Ni3+/Ni2+ and Co3+/Co2+ coexisted in NCO-NNA and the average oxidation states of Ni and Co were ~2.25 and ~2.64, respectively, which agree well with the earlier report [23].
c EDS mapping of O, Co, and Ni in NCO-NNA Fig. 3 XPS spectra of a O 1s, b Ni 2p, and c Co 2p for NCO-NNA.
It seems that the relatively broader diffraction peaks of NCO-NNA in comparison to those of NCO-P are largely due to the presence of smaller nanocrystals in NCO-NNA as well as a relatively smaller weight of the oxide deposited on the Ni substrate.
In this case, the presence of the MM2 motif and the absence of exonic sequence would facilitate the formation of DSBs that are destined for CO and DSBs that occur independent of these sequence characteristics would be more likely to result in NCOs.
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