Sentence examples for in multiple extended from inspiring English sources

Gene mapping studies in multiple extended families with early-onset breast and ovarian cancer led to the identification of the BRCA1 and BRCA2 genes as harboring germline breast and ovarian cancer risk mutations.

The central finding described here is that some of the Crenarchaeota and Korarchaeota possess actin-like proteins that are not only monophyletic with the eukaryotic actin family but also are structurally similar to Arp2/3 in that they contain multiple, extended inserts between core structural elements that are missing in eukaryotic actins.

Initially children whose parents served in the military experienced one deployment; now the majority of children experience multiple, extended deployments.

MDR ADH origin(s), at a fourth stage, may also be further resolved in multiple or extended modes, but the classical liver MDR ADH of the liver type can still be traced to a gene duplication ∼550 MYA (million years ago), at the early vertebrate radiation, compatible with the post-eon-shift, "Cambrian explosion".

A raised erythrocyte sedimentation rate (ESR) at inclusion and AUC DAS28 at six months increased the hazard rate of CVE independently whilst DMARD treatment was protective in multiple Cox extended models adjusted for sex and CV risk factors.

Patients with systemic-onset JIA, psoriatic arthritis, enthesitis-related arthritis, and oligoarticular arthritis who later develop arthritis in multiple joints (extended oligoarticular JIA) can all have polyarticular disease, but they are all excluded from the polyarticular JIA subgroups based on the ILAR classification.

Vessels within the tumor demonstrated high levels of ITGB1 in multiple layers extending from the endothelium through the media and into the adventitia (Fig.  1h).

Finally, in multiple myeloma, ZA extended median OS by 5.5 months (P=0.04) vs clodronic acid and increased median PFS by 2 months (P=0.0179) (Morgan et al, 2010).

In order to check whether the regulation role of GC content in splicing is a universal phenomenon in multiple species, we extended our work on humans to nematodes, fruit files, and mice.

This capacity to bind to the same ligand in multiple orientations also extends to other multidrug-binding proteins, all of which appear to be characterized collectively by voluminous pockets that predominantly employ aromatic stacking interactions for ligand binding.

Recently, extended target tracking is a hot topic in the field of data fusion and has drawn a considerable attention, especially the multiple extended-target tracking (METT) [8 14].