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Further consideration needs to be given to the importance of PF alignment, preferably in more functional positions than supine and non-weight-bearing, and in longitudinal evaluations.
In more functional approaches, only CD14-low expressing CD16+ monocytes (so called CD14dim cells) displayed characteristics of murine Ly6Clo monocytes [ 19].
Tavtigian et al (2001) postulate that the Leu217/Thr541 haplotype results in more functional disruption of the protein than the commoner Leu217/Ala541 haplotype.
This may be explained by the fact that most chronic diseases are progressive in nature, resulting in more functional limitations over time.
This result revealed gender differences for genes in more functional groups than formerly published [ 12], where mainly transport and drug metabolism genes were found to be differentially expressed by gender in kidneys of adult mice.
103 The goals for each of these risk factors should also be adjusted to the patient's preferences, life expectancy, and cognitive status, with a more aggressive approach being adequate in more functional individuals.
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Another assumption is, that essentially replacing murine apoA-I with human apoA-I in these studies resulted in a more functional HDL that inhibited atherosclerosis, and that wild-type and Milano did not differ in this effect.
In both cases, the DNA must be stabilized in a more functional conformation.
There is huge potential, but architects are only just beginning to learn how to apply biomimetics in a more functional way, says Michael Weinstock, director of the Architectural Association School of Architecture in London.
Apparently, the lipofuscin-correlated transcripts were overrepresented in many more functional pathways than the 1000 FDR-ranked chronological genes, resulting in an increase in the number of functional (mostly immune-related) pathways.
"Many people think of clothes in a more functional way.
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