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In a recent study an increase of PPARγ expression in comparison to normal mucosa it has been observed in 25% (four) of patients with colorectal tumour [ 23] These contrasting results could be attributed to differences in methodological procedures as well as to the number of patients analyzed.
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All agreed to participate in the methodological procedures proposed in the research, approved by the ethics committee of the Center for Health Sciences UFPB under protocol number 135/10.
This paper incorporates that in its methodological procedures and improves the classic way of classifying licenses based on Lerner and Tirole2's work in a more realistic, empirically-based schema.
The first is to systematically locate and profile available resources, in terms of theoretical guidelines and methodological procedures, in the extant literature in order to guide new research endeavours in this area.
Data collation and summarization was done in two steps, as recommended methodological procedures found in the literature [ 38, 40].
Such comparisons have been conducted previously regarding their philosophical assumptions and orientations, key elements of case study research, their range of application, and the lacks of methodological procedures in publications.
The F2 number is significantly higher than a priori expectations based on extrapolated BXD data (PYates corrected χ2<<0.0001) and argues that the methodological procedures in the BXD analysis offer sufficient protection against Type 1 error in this study.
The paper is organized in the following sections: section 2 describes the source of data and methodological procedures applied in this paper.
Finally, we will summarise the methodological procedures employed in the studies and highlight some available resources in this area.
This study required development and implementation of methods appropriate to analysis of data collected in a complex sampling framework and methodological procedures to ensure scientific rigor in a highly public and politicized environment.
Methodologically applied our experimental design is based on a multi-method approach, understood as a form of research in which two or more methodological procedures for the investigation on the same object of study through the different moments of the course of the investigation are used.
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