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The regulation of MMP expression is complex, involving a multitude of transcription factors and histone deacetylases [ 27- 31]; however, no information is available regarding the negative regulation of MMP genes in mechanisms that reduce ECM degradation.
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Finally, we demonstrated experimental conditions in which mechanisms that reduce oncogene activation may arise rapidly.
The investigators say that certain medication errors in children can be reduced or prevented by computerizing drug orders with built-in double- and triple-checking mechanisms that reduce the likelihood for miscalculation or misinterpretation, something that the Johns Hopkins Children's Center is already doing.
Previous research indicates that certain medication errors in children, and adults, can be reduced or prevented by computerizing drug orders with built-in double- and triple-checking mechanisms that reduce the likelihood for miscalculation or misinterpretation, a procedure that Johns Hopkins Children's Center follows.
Observations of reduced sodium-hydrogen exchanger activity in the proximal tubule [ 44] and increased medullary blood flow [ 45, 46] in response to acute and chronic increases in blood flow point to mechanisms that reduce sodium reabsorption.
The potential for competition and selection during zygote formation and seed maturation has been characterised in flowering plants [ 1, 2], and in many angiosperms, pollen selection mechanisms that reduce inbreeding depression and promote outcrossing have evolved [ 3].
We show that starved flies are attracted to high concentrations of vinegar partly due to neuromodulatory mechanisms that enhance sensitivity in Or42b ORNs, an attractive odor channel, and partly through neuromodulatory mechanisms that reduce sensitivity in Or85a ORNs, an aversive odor channel.
In Section 3, we discuss some mechanisms that reduce energy consumption, which fall into the category of cell layout adaptation (CLA) techniques.
Over the past decade, β-blockers have been proven to reduce mortality in patients with heart failure by mechanisms that reduce catecholamine-driven myocardial apoptosis, fibrosis, and remodeling (2, 5, 10).
The results from this study could be used in the design of new lever propulsion mechanisms that reduce the risks of secondary shoulder disorders and increase user's comfort.
The empirical mechanism by which E. coli regulates its growth rate is in agreement with our theoretical finding, suggesting that metabolic adaptations to environmental challenges require active mechanisms that reduce growth rate in order to increase the repertoire of responses.
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