Sentence examples for in maximum concentration from inspiring English sources

There also was a decrease in maximum concentration (Cmax) when Neoral was given with olestra compared with giving Neoral alone (1,202 ng/mL versus 876 ng/mL; P =.015).

In comparison to the fasting state, the low fat breakfast was related to 2.67-fold increase in AUC and 2.42-fold increase in maximum concentration (Cmax).

Differences in maximum concentration (Cmax) and Area Under the plasma ivermectin concentration-time Curve (AUC∞) between treatments were analyzed with analysis of variances by JMP statistical software (ver. 11, SAS Institute Inc., www.jmp.com).jmp.com

Simulations predicted a consistent exposure (i.e., no substantial changes in maximum concentration) to rivaroxaban during the transition from 15-mg twice-daily to 20-mg once-daily dosing (Fig.  6).

There is an increase in AUC and t1/2 for telavancin and a decrease in CL with increasing renal impairment, but no substantive change in maximum concentration after a single-dose administration.

The coadministration of the two drugs did not affect chloroquine or desethylchloroquine pharmacokinetics but increased plasma primaquine concentrations significantly (P ≤ 0.005); the geometric mean (90% confidence interval [CI]) increases were 63% (47 to 81%) in maximum concentration and 24% (13 to 35%) in total exposure.

The increase in maximum concentrations was smallest for the strongest competing metals (Cu and Ni).

Coadministration of chloroquine with primaquine resulted in a 63% increase in maximum concentrations and a 24% increase in total exposure to primaquine.

Plasma concentrations of primaquine were increased significantly with a 30% increase in maximum concentrations and a 15% increase in total exposure, reflecting the contraction in the volume of distribution with only a slight reduction in the elimination rate.

A second remarkable difference between injection and pour-on results is that for the pour-on application, there is no significant difference in maximum concentrations for the four steroids determined.

Unlike many other amino acids, BCAAs are metabolized only in skeletal muscle, since the BCAA amino-transferase enzyme is not present in the liver, the site in which the enzymes metabolizing all other amino acids are present in maximum concentrations, and up to 58% of all the amino acids ingested (except BCAA) can be oxidized in the liver on the first pass.