This stochastic simulation study investigated whether genomic selection can be effective in preserving a major quantitative trait locus (QTL) allele from a donor line during the backcrossing phase.
In rice, a major quantitative trait locus (QTL) for P-deficiency tolerance, P uptake 1 (Pup1) was mapped to a 150-kb region of chromosome 12 containing 60 predicted genes (Wissuwa et al., 2002; Chin et al., 2011).
Quantitative trait loci (QTL) analysis using a F2 population (n = 150) from a cross between SA30199 and Borung revealed that resistance to CPA is controlled in part by a major quantitative trait locus (QTL) on chromosome 2, explaining 39% of the antibiosis resistance.
The other interval reported as under selection in commercial broilers is chr4 71,720,000-71,860,000, containing the TBC1D1 gene, which had earlier been identified in several independent studies as the major Quantitative Trait Locus (QTL) explaining differences in growth between broilers and layers.
These results demonstrate that there are major quantitative changes in leptin responsiveness between obese and lean adipocytes during differentiating stages, but not differentiated stages, of hAT in vitro.
There is a major quantitative effect in the mutant (and see below) but as the arousal enhancement is not eliminated, this bold statement is incorrect.
Our data, however, show a major quantitative difference in the extent of oxidative injury between MS lesions and the majority of the studied experimental models of CNS inflammation and demyelination.
In each case, the gene clusters were in the vicinity of previously identified major quantitative trait loci for the corresponding trait.
A minimum of 15 known genes, in addition to a relatively few major quantitative trait loci, are identified as being critical to the domestication process.
