Exact(2)
However, because of a lower number of children than in main trial and loss of statistical power, we observed only a trend toward increased carriage of nonvaccine-type pneumococci (p = 0.08) at 24 months of age.
When stratified by recruitment time (vanguard v main trial; data not shown), participants in the intensive arm recruited during the vanguard phase had similar rates of HMA to participants in the intensive arm of the main trial in most years except the initial year, where the rate of HMA in vanguard participants was 5.62% and in main trial participants was 3.12%.
Similar(58)
A total of 1000 patients were to be recruited over a 3-year period in the main trial in order to have 80% power to detect an increase in RFI from 70% to 77.9% (α 0.05, two sided).
Patients in six of 45 centres in the main trial were approached to take part in the sub-study.
None of the schools or teachers who were involved in the feasibility and pilot work was included in the main trial, which is presented in this paper.
Parameters of nutritional status analysed in the main trial were considered in this analysis.
In the main trial no difference in screening uptake was found between participants who received the informed choice invitation and those receiving the standard invitation [ 15].
There were no maternal demographic differences between the subset of women in this study and those in the main trial population (13).
To verify representativeness, a questionnaire on methods of delivering chemotherapy was posted to research nurses and pharmacists in all other centres participating in the main trial.
Because it was not possible to blind the participants in this pilot trial (nor in the main trial), both groups were fully informed of the main trial's hypothesis/research question: Does increased hydration reduce progression of CKD?
Bemba and four others are also on trial in a second case in which they are accused of bribing witnesses in his main trial.
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