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Retroperitoneal lymph node dissection (RPLND) in low stage disease is considered an optional staging procedure and templates have been introduced to avoid the risk of postoperative loss of antegrade ejaculation.
Additionally, although the difference was not statistically significant, p27 was dominantly expressed in low stage tumors.
Similarly, CXCL1 combined immunostaining score was higher in high stage tumors (T2-T4) than in low stage tumors (Ta-T1) (p < 0.0001).
From choice the diagnosis of OGCT should be confirmed histologically, either from oopherectomy in low stage disease or by biopsy in advanced disease.
Perinecrotic HIF-1α expression retained its prognostic significance in the subgroup of low stage, while significance was lost in stage III/IV patients, indicating that HIF-1α expression seems to be especially important in low stage patients.
Furthermore, this risk category tended to be valid in low stage (p = 0.059) and high stage (p = 0.006) subgroups, as well as in the low IPI (p = 0.055) and high IPI subgroups (p = 0.034) (Table 3).
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Because the vast majority of our patients were not in need of treatment and low staged at diagnosis, our results suggest that serum sTACI could be a new, easily assessed, marker for predicting CLL behaviour in low staged patients.
The clinical significance of the detection of CTC in low stages of nonmetastatic rectal cancer in patients treated with short-term preoperative radiotherapy is so far unknown (not determined).
It might be a predictive marker for metachronous liver metastasis even in low-stage stomach cancers.
In some neuroblastomas, preferential ICAD expression is observed in low-stage, but not in their high grade [ 12].
This suggests that 17q gain as a prognostic factor plays a more crucial role in low-stage tumours.
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