This is in line with the mode of action of Bt strains as their protoxins upon ingestion by the target insect pests take about 48 to 72 h to be converted into toxic protein crystals which further bind with midgut epithelial cells and cause mortality (septicemia) symptoms (Bravo et al. 2017).
The Tories' Brexit agenda was never about restoring sovereignty to ordinary people – its purpose is to deregulate the British economy and bring us more in line with the American mode, permanently shifting the balance of power in society.
This observation is in line with the irreversible mode of binding of afatinib.
The decrease in cathepsin K activity observed under TLN treatment is well in line with the known mode of action of the drug at reducing osteoclastic activity [ 9, 10].
In line with the predicted mode of IL-1 α's alarmin function (Dinarello, 2009; Cohen et al, 2010), PDT-dependent cell damage mobilised the release of this IL-1 from a pre-existing intracellular pool.
In the systemic rat adjuvant arthritis, in contrast, IL-1β is far more elevated in the LN than in the SM [ 19], in line with the different mode of induction of the disease, which favors spread of the arthritogen to the regional LNs [ 23].
This suggests a non-synergistic effect, which is in line with the assumed mode of action of Qnr proteins as well as with earlier susceptibility determinations showing that isolates carrying two qnr genes do not display a superior resistance phenotype [ 24, 25].
The molecular data were in line with this mode of transmission but could not fully confirm it because of the known low variability of the B19 genome especially in the VP1/VP2 gene.
Experimental data published so far for SUP [ 30, 31] and for the two petunia proteins [ 24, 38, 39] revealed a peculiar DNA recognition mechanism that is only partially in line with the canonical binding mode of tandem ZFs [ 8].
Having established the conditions for modal transfer from a car journey, an analytical methodology was devised for calculating the potential of transfer to each possible alternative mode, in line with the diagram in Fig. 1.
