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The results of 68Ga-DOTAVAP-P1 were in line with the expression of luminal VAP-1, which was high at the site of inflammation [39].
The transcripts of all genes were present from day 1 until at least 7 days after inoculation (Fig. 2; Additional file 1: Figures S1, S2, S3), in line with the expression of ustR (Fig. 1).
Such view is also in line with the expression of CXCR7 on the heart valves of adult mice.
The changes in MMP-2 and MMP-9 activity were well in line with the expression of protein in the brain.
The data obtained by the analysis of individual recombination events using SHR trap lines are in line with the expression of several genes known to encode for protein factors involved in homologous recombination.
In our experiment, we found the expression of MMP-2 and MMP-9, both in latent form, increased in the brain of PBS-treated EAE mice, and the changes in MMP-2 and MMP-9 activity in CSF were well in line with the expression of protein, which are coincided with previous reports [37].
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In line with the membrane expression, the intracellular (ic) expression of MICA and MICB was significantly reduced in H1339 and MDA-MB-231 cells by NZ28 (Fig. 1d).
In line with the gene expression results, enhanced GFAP protein expression has been detected within days after SE in the hippocampus of various experimental epilepsy models in the immature (P15 P21) [7], [52], and adult rats [38], [53], [54].
By contrast, in the category "immunity", the number of genes in the SAE-enriched category was higher than expected but distribution of expression level was in line with the average expression of all genes.
In line with the mRNA expression change, TLR2, TLR3 and TLR4 protein expression was also increased in a dose-dependent manner after IL-29 incubation.
Longer relapse-free survival has previously been reported for patients with higher expression of FMO5 [23] which is in line with the observed expression of FMO5 in our study.
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