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In order to maximize the stringency of the selection scheme, our method employed a fourfold combination of negative/positive selection measures, comprising ganciclovir (negative) [27] and blasticidin selection of stable selection cell lines (Fig. 1a) in line with selection of the shRNA library via puromycin, and EGFP fluorescence (positive), respectively.
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While some aspects are in line with balancing selection, parallel directional positive selection favouring all slow causing mutations cannot be ruled out, as was first proposed by Patin et al. [8] when considering the *5 series alone.
By the way, the choice Im(ε M ) > 0 is in line with the selection of the outgoing waves in the absence of energy sources [4, 16, 23, 33].
Instead evidence is in line with balancing selection acting on personality traits, probably supported by human tendencies to seek out, construct and adapt to fitting environments.
However, for two participants, the responses were in line with their selection.
This result is in line with the selection of certain quasicrystalline alloys for the industrial production of low-stick cookware that was secured in patents by one of us long ago [11, 12].
While the miniaturization effect is in line with the selection for economy model, the effect observed on genes with high EB, in Arabidopsis, is in apparent striking contrast with observations in other systems.
Because of the clear functional basis of RNA editing demonstrated above, we suspected that RNA editing would increase in line with the selection constraint on genes.
In this way, they have successfully demonstrated that coevolution between marked strains of P. fluorescens and phage Φ2 in soil is more in line with fluctuating selection than arms-race dynamics, as neither the bacteria nor phage become increasingly resistant/infective over time.
These findings are in line with the "selection for economy" model stating that widely-expressed gene loci are compact due to strong pressure for shortening non-coding regions and this might explain why they rely on tele-enhancers for transcription activation (Eisenberg and Levanon 2003; Pozzoli et al. 2007; Vinogradov 2006).
In line with the kin selection theory [23] and similar to capuchin monkeys [7], female long-tailed macaques behave pro-socially towards kin and are more pro-social towards kin than towards non-kin, reflecting the importance of their kin-relations [17], [but see 24].
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CEO of Professional Science Editing for Scientists @ prosciediting.com