The UVP PD methodology presented may serve as an in-line tool for non-invasive, real-time monitoring and process control.
Hence, we demonstrate the feasibility of a method which uses IR spectra from intact cells that may be employed in a second step as an in-line tool in process development and process control along Quality by Design principles.
It was concluded that an in-line tool such as Raman spectroscopy is a simple and sensitive technique able to assist in both formulation optimization and process development.
This paper presents two different methods for combining imaging and CLD data obtained with in-line tools in order to get reliable estimates of particle size distribution and aspect ratio, where the imaging data is used to constrain the search space for an aspect ratio from the CLD data.
A lyophilization process is usually only specified in terms of a 'recipe' (shelf temperature and chamber pressure vs. time); according to the recent PAT guidelines issued by FDA, there is the need to develop in-line tools to enable better monitoring and control freeze-drying.
Currently, Amazon does not offer a built-in command line tool to facilitate the high-throughput transfer of large files between S3 and an EC2 instance.
Users can save thresholding configurations for later use in the GUI or in the command line tool.
For quantitative experiments, the length of overlap of junctional complexes was measured in a masked fashion in images of EC junctions in the choroid using the broken line tool in ImageJ Abramoff et al., 2004.
The output of the drainage network is smoothened using a smooth line tool in ArcGIS-9.3.
The output of the stream network is smoothened using a smooth line tool in ArcGIS 10.
We also measured the arclength of the leading edge by using the segmented line tool in the Image J software (NIH) from the phase contrast videos.
