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However, a lack of common HBV integration site in other samples cannot rule out the possibility of common origin of these two tumor components, especially in light of the data from WES analyses, because HBV could integrate in any sites of tumor genome.
Respondents were invited to score the questions in light of the data from the first round using a Likert scale.
However, this seems unlikely in light of the data from our laboratory [ 29] that myoepithelial carcinomas, which are generally aggressive, show fewer genetic alterations.
DOI: http://dx.doi.org/10.7554/eLife.06205.019 In light of the data from yeast, we considered that the trends noted above could be caused by the underlying chromatin environment, with H3K4me3 antagonizing and H3K36me3 promoting de novo DNA methylation.
However, in light of the data from the Y2H system, it is equally possible that the interaction between dysbindin and TRIM32 (and the mutants) in HEK cells is mediated by a 'bridging' protein or post-translational modification that is not present in yeast.
Although this may be a consequence of different PKCι-dependent signalling pathways in the different cell lines, in light of the data from the exogenous expression of PKCι activity mutants, this supports the role of required thresholds of PKCι abundance/activity.
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The widespread preparedness for an influenza pandemic that has resulted from the prevalence of H5N1 therefore remains appropriate even in light of the data we present.
In light of the above data, it is highly relevant to investigate levels of histone and tubulin acetylation in material derived from PKAN patients.
In light of limited data from interventional trials, what could be the rationale for early insulin supplementation?
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