Testing this same concept in a more stromal-targeted therapy (e.g. hormonal manipulation) did not produce significant differences, suggesting that a short delay in onset is of less importance in this therapeutic strategy.
Pollen allergens on the other hand, appear to be important in the USA, but of less importance in Europe [ 2, 14].
Lung function was not measured, which would have been valuable in patients with COPD [ 21], but of less importance in patients with asthma [ 24] in order to identify the risk of ER visits.
Finally, there may be biological interactions between the individual components of the MetS in women and not or of less importance in men.
Our findings could also be interpreted such that differences in basal oestrogen levels are of less importance in a modern real-life clinical setting where aggressive intensive care resuscitation protocols may diminish any relative advantage of a premenopausal female hormone profile [ 15].
Another possibility is that individual perceptions of health and quality of life shift in the 'oldest old', 23 which could render health factors of less importance in explaining suicidal feelings in extreme high age.
The secondary and tertiary sectors have less importance in indigenous communities than in other societies and, again, in all cases, the self-employment rate is higher for the indigenous population than for the non-indigenous population.
Anxiolytic premedication before non-ambulatory surgery in adult patients may have become of less importance in an era of better preoperative patient information.
For instance, an uncharacterised activation mechanism involving another NADPH-oxidase homolog, AtrbohD, is also active in ABA-induced stomatal closure, although of less importance in this process, as shown by mutant studies [ 19].
There was no reduction in testis size following mating and therefore testis size appears to be of less importance in determining male mating frequency in this species.
