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Transcranial magnetic stimulation, the other type of stimulation being tested for migraines in large trials, does not require a surgical procedure.
Some of the first gels tested in large trials included Ushercell, which was made up of cellulose sulfate, and PRO 2000, which contained a polymer of naphthalene sulfonate.
To find out whether screening saves lives, they say investing in large trials that can determine overall mortality is "worth the expense compared with the continued cost of supporting widespread screening campaigns without knowing whether they truly benefit society".
Dr. Michael Davidson, clinical professor and director of preventative cardiology at the University of Chicago, said that because of torcetrapib's failure, the Food and Drug Administration would not approve any CETP inhibitor until it had been tested in large trials to prove it reduces the risk of death and heart attacks.
Experts said the findings were interesting and called for the idea to be tested in large trials.
This was a small study; thus, the clinical value of this test can only be established in large trials.
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If more software patents are allowed, and survive litigation and IPR/CBM proceedings and result in large trial verdicts, we could see a renewed interest in patent portfolio building by high-tech and software companies.
For the drug to be approved, Lilly will need to replicate the results in larger trials.
Even if the drug works in larger trials, it will be several years before it wins approval.
In a small study, since repeated in larger trials, they compared blood samples from six people who felt socially isolated with samples from eight who didn't.
Some critics say that for the test to be accepted, the Lancet data must be reproduced by others and the technique tested in larger trials.
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