The self-nonself discrimination principle is employed, in particular, by the restriction-modification (RM) systems, which are probably the best characterized defense systems in prokaryotes, to a large extent, because restriction endonucleases are essential experimental tools of molecular biology [ 8- 10].
However, such measures have not succeeded in stopping the current epidemic in West Africa -- to a large extent because they were initiated too slowly and at an insufficient scale.
When you look at the situation in Ukraine at the moment, it was brought about to a large extent because of the failures in Russia and Ukraine, where there has been a hugely widening gap between rich and poor.
"We are painfully aware of how Earth's complex systems are in danger of breaking down, to a large extent because of how we humans have exploited Earth's resources and have ignored the ways in which we pollute the air, the water and the soil," said Bill Breakey, a member of the church's Environmental Stewardship Action Group.
If this gets written up as a triumph for him in tomorrow's papers, it will be to a large extent because of his willingness to listen to MPs and engage with his critics.
The disparity arises to a large extent because the distribution of human cases in China's provinces does not match that of outbreaks reported in domestic poultry.
The volume of SMS in Pakistan grew by 253 percent between 2009 and 2010, to a large extent because of mobile-marketing.
Unlike arsenic, salinity could be managed to a large extent because people can feel the change of the salinity level in drinking water by taste.
"To a large extent because of what I witnessed, we may do something like that on July Fourth in Washington down Pennsylvania Avenue," Trump said.
Productivity has slowed to a large extent because hiring is growing faster than capital investment.
