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The FDA report stated that canine DCM was typically caused by a genetic predisposition in large breed dogs such as Great Danes and Newfoundlands.
Degenerative lumbosacral stenosis is a common problem in large breed dogs.
Gastric dilatation-volvulus (GDV) is a life-threatening condition of mammals, with increased risk in large breed dogs.
It is concluded that this technique can be included in a normal echocardiographic examination in large breed dogs under clinical conditions.
Non-ambulatory tetraparesis with an absence of the dens of C2 (axis) has not previously been reported in large breed dogs.
Therefore, we previously investigated the feasibility of pedicle screw-rod fixation (PSRF) in a cadaver study [ 14, 15] and in an in vivo pilot study [ 14] in large breed dogs.
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Hip dysplasia is a hereditary condition in dogs, especially in large breeds such as the German shepherd, Old English sheepdog, and Saint Bernard.
The preoperative finding of hip dysplasia in the majority of dogs used in this study suggests that hip dysplasia may be common in hounds purpose-bred for research, and several groups have suggested that canine hip dysplasia is a complex genetic trait with high prevalence in large breeds.
Osteosarcomas are common malignancies in large breeds of dogs.
In the group of purebred dogs, the percentage of CMSs was higher in large breeds (38.7%, n = 12), i.e. German Shepherds (n = 4) and Rottweilers (n = 2), and single CMS cases were noted in the following breeds: St. Bernard, Tosa Inu, Doberman Pinscher, Flat Coated Retriever, Labrador Retriever and German Shorthaired Pointer.
This is most common in large breeds of dogs such as Rottweilers, German Shepherds, Labradors, and Great Danes.
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