Sentence examples for in joint damage from inspiring English sources

Inflammatory mediators, such as cytokines and free radicals, produced by infiltrating inflammatory cells, play a critical role in joint damage [3], [4].

Rheumatoid arthritis (RA) is a chronic inflammatory disease resulting in joint damage.

Owing to their aggressive, intrinsically activated phenotype, RASF are active contributors in joint damage.

DNA methylation could play a critical role in joint damage by epigenetic imprinting FLS in RA.

Thus, this outcome indicates a relative increase in joint damage and is unit-free.

It usually takes at least one year before significant changes in joint damage can be observed.

Msi1 protein expression was significantly higher in joints damaged by CIA than in those with no lesions (P < 0.0001) and was related to the severity of the lesions (Spearman's rho = 0.775, P = 0.0001).

The aim of this study was to analyze its role in radiological joint damage in rheumatoid arthritis (RA).

Interestingly, CP690,550 was shown to be effective in preventing joint damage in collagen-induced arthritis (CIA), an animal model of rheumatoid arthritis [ 26].

Studies have shown that adalimumab is effective in preventing joint damage in early RA [ 15] and improving clinical and laboratory parameters, emphasizing the pivotal role of TNFα in this pathology.

To compare the effectiveness of RTX against anti-TNF agents in preventing joint damage in patients with RA who have experienced inadequate response to at least one prior anti-TNF agent.