Sentence examples for in its sequestration from inspiring English sources
First, we showed that Rab4b is mainly located with GLUT4, in its sequestration compartment and in TfR containing endosomes.
When Rab4b expression is decreased, intracellular GLUT4 is mainly in its sequestration compartment thus suggesting that trafficking between endosomes and the sequestration compartment occurs.
Altogether, our results documents Rab4b as the first Rab protein which co-localize in adipocytes with GLUT4 in its sequestration compartments which is modulated in diabetes.
ST and nicotine treatment also resulted in induction of Bad and Bax phosphorylation, increased the association of Bad with 14-3-3ζresulting 14-3-3ζresulting 14-3-3ζresultinglasm of head and neck cancer cells, thus blocking its pro-apoptotic function.
In addition to chitin binding, mosquito proteins with CBDs have also been described to bind heme and have a role in its sequestration during blood digestion [ 50].
This suggests that the expression of MUC4 promotes binding of Bad with 14-3-3 14-3-3 14-3-3thereby helproteinss sequestrandon in therebyosol.
Although not all levels of regulation of the Cdc14 phosphatase in budding yeast may yet be understood, its dominant and most striking control is exerted via its sequestration in the nucleolus by its inhibitor Net1 (also called Cfi1) [ 14,15].
The absence of PCNA at replication centers due to its sequestration in ΔNLA-lamins aggregates in a dominant-negative manner may lead to stalled replication forks; collapse of the replication forks may result in DSBs [ 59].
Moreover, MEK-ERK activation might be responsible for the increased phosphorylation of the pro-apoptotic protein Bad leading to its sequestration in the inactive form in the cytoplasm by binding to protein 14-3-3 14-3-3 14-3-3., 1999).
Also, in these cells WWOX colocalization with ΔNp63 α lead to its sequestration in the cytoplasm.
These observations indicate that Rab4b is present in the compartments where GLUT4 is mainly localized in basal condition i.e its sequestration compartment and also in TfR containing endosomes.
